A cytocompatible microporous Sr-doped titanium dioxide coating fabricated by plasma electrolytic oxidation

Titanium has broad application prospects in the field of hard bone tissue repair and replacement due to its low density, an elastic modulus similar that human bone, better biocompatibility than stainless steel cobalt-based alloys. However, titanium is a biologically inert material with biological activity. After implantation, it only physically bonds instead chemically bonding, which causes complications such as implant loosening. In this study, strontium-doped dioxide coating was prepared on surface micro-arc oxidation. Based systematic study properties coating, bioactivity were evaluated vitro cell experiments. The results showed successfully exhibited strong bonding substrate. had porous structure, strontium dispersed inside coating. ions released slowly, improved corrosion wear resistance titanium. experiments good compatibility; promoted adhesion, proliferation differentiation MC3T3-E1 cells These preparation by oxidation feasible. morphology, activity potential for clinical application.